SECURITIES AND EXCHANGE COMMISSION
                              Washington, DC 20549

                                 Amendment No. 1

                                   FORM 8-A/A
                                   ----------

                FOR REGISTRATION OF CERTAIN CLASSES OF SECURITIES
                     PURSUANT TO SECTION 12(b) OR (g) OF THE
                         SECURITIES EXCHANGE ACT OF 1934

                               Celsion Corporation
- --------------------------------------------------------------------------------
             (Exact Name of Registrant as Specified in Its Charter)

                  Delaware                            52-1256615
- ------------------------------------------   --------------------------------
          (State of Incorporation                  (IRS Employer
              or Organization)                   Identification no.)

10220-I Old Columbia Road, Columbia, Maryland                 21046-1705
- ---------------------------------------------     ------------------------------
   (Address of principal executive offices)                   (Zip Code)

If this form relates to the                 If this form relates to the
registration of a class of                  registration of a class of
securities  pursuant                        securities  pursuant
to Section 12(b) of the                     to Section 12(g) of the
Exchange  Act  and is                       Exchange  Act  and is
pursuant to General  Instruction            pursuant to General  Instruction
A.(c),  please check the                    A.(d),  please check the
following box. [ ]                          following box. [ ]


Securities Act registration statement
file number to which this form relates:
                                               --------------------------
                                                     (If applicable)

Securities to be registered pursuant to Section 12(b) of the Act:

         Title of Each Class                 Name of Each Exchange on Which
         to be Registered                     Each Class is to be Registered
- -------------------------------------    --------------------------------------


- -------------------------------------    --------------------------------------

Securities to be registered pursuant to Section 12(g) of the Act:

                         Preferred Share Purchase Rights
- --------------------------------------------------------------------------------
                                (Title of Class)

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         Explanatory   Note:  This  Amendment  No.  1  amends  the  Registration
Statement  on Form 8-A of Celsion  Corporation  (the  "Company")  filed with the
Securities and Exchange Commission ("SEC") on September 19, 2002 (as so amended,
the  "Registration  Statement") in connection with the Company's  listing of its
Preferred  Share  Purchase  Rights on The American Stock  Exchange.  Capitalized
terms used  herein and not defined  have the  meanings  ascribed  thereto in the
Registration Statement as originally filed.

          This  Amendment  No. 1 is being filed to reflect the  amendment of the
first  sentence of the  definition of "Acquiring  Person" in Section 1(a) of the
Rights  Agreement,  and to include as an exhibit to the  Registration  Statement
Amendment No. 1 to Rights Agreement,  dated as of August 15, 2002,  effective as
of January 16, 2003 (the "First Amendment"). Except as amended hereby, there are
no other changes to the Registration Statement.

Item 1.  Description of Securities to be Registered

         Effective  as of January  16,  2003,  the  Company  effected  the First
Amendment. Pursuant to the First Amendment, the definition of "Acquiring Person"
appearing  in Section 1(a) of the Rights  Agreement  has been amended to provide
the following  additional  exclusion to the  definition  of "Acquiring  Person",
subsequent to item (iii) of the first  sentence of that Section,  to be numbered
as item (iv) of such sentence:

                  (iv) Boston Scientific Corporation ("BSC") shall not become an
                  "Acquiring  Person" as the result of the acquisition of shares
                  of Common  Stock by BSC solely (a)  pursuant  to that  certain
                  Transaction  Agreement,  dated as of January 20, 2003,  by and
                  between the Company and BSC (the "BSC Transaction  Agreement")
                  and (b) pursuant to a stock  dividend on,  subdivision  of, or
                  similar   proportionate   adjustment  in   (collectively,   an
                  "Adjustment"), the shares of Common Stock received pursuant to
                  the BSC Transaction Agreement,  provided, however, that if BSC
                  shall  become the  Beneficial  Owner of an aggregate of 15% or
                  more of the shares of Common Stock then  outstanding by reason
                  of  share   acquisitions   other  than  pursuant  to  the  BSC
                  Transaction  Agreement or an Adjustment in the shares received
                  pursuant  thereto  (provided  that such  aggregate may include
                  shares  of  Common   Stock   acquired   pursuant  to  the  BSC
                  Transaction  Agreement or any  Adjustment),  then BSC shall be
                  deemed to be an "Acquiring Person".


         The foregoing  description of the Rights  Agreement is qualified in its
entirety by  reference  to the full text of (a) the Rights  Agreement,  which is
attached as Exhibit 4.1 to the Registration  Statement, as originally filed, and
incorporated  herein  by  reference,  and  (b) the  First  Amendment  to  Rights
Agreement attached hereto as Exhibit 4.2 and incorporated herein by reference.

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Item 2.  Exhibits

Exhibit No.       Description

4.1 *             Rights Agreement dated as of August 15, 2002,  between Celsion
                  Corporation and American Stock Transfer & Trust Company, which
                  includes  as Exhibits  A, B and C,  respectively,  the Form of
                  Certificate   of   Designations   for  the   Series  C  Junior
                  Participating  Preferred Stock, the Form of Right Certificate,
                  and a Summary  of the Rights  (incorporated  by  reference  to
                  Celsion  Corporation's Current Report on Form 8-K filed August
                  21, 2002)

4.2 **            First  Amendment  to Rights  Agreement  dated as of August 15,
                  2002 between Celsion Corporation and American Stock Transfer &
                  Trust  Company,  as Rights Agent,  effective as of January 16,
                  2003.

* Previously filed by Celsion  Corporation on Form 8-A on September 19, 2002. **
Filed herewith.

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                                    SIGNATURE

         Pursuant to the  requirements of Section 12 of the Securities  Exchange
Act of 1934, the registrant  has duly caused this  registration  statement to be
signed on its behalf by the undersigned, thereto duly authorized.


        CELSION CORPORATION

           By:  /s/  Anthony P. Deasey
                ---------------------------------------------------------
                     Anthony P. Deasey
                     Executive Vice President--Finance and Administration
                     and Chief Financial Officer

                                       4


Date:    February 11, 2003








                                  EXHIBIT INDEX


Exhibit No.       Description

4.1 *             Rights Agreement dated as of August 15, 2002,  between Celsion
                  Corporation and American Stock Transfer & Trust Company, which
                  includes  as Exhibits  A, B and C,  respectively,  the Form of
                  Certificate   of   Designations   for  the   Series  C  Junior
                  Participating  Preferred Stock, the Form of Right Certificate,
                  and a Summary  of the Rights  (incorporated  by  reference  to
                  Celsion  Corporation's Current Report on Form 8-K filed August
                  21, 2002)

4.2 **            First  Amendment  to Rights  Agreement  dated as of August 15,
                  2002 between Celsion Corporation and American Stock Transfer &
                  Trust  Company,  as Rights Agent,  effective as of January 16,
                  2003.

* Previously filed by Celsion  Corporation on Form 8-A on September 19, 2002. **
Filed herewith.

                                       5

                               CELSION CORPORATION

                                 AMENDMENT NO. 1
                                       to
                                RIGHTS AGREEMENT
                           Dated as of August 15, 2002

         This  Amendment No. 1 (this  "Amendment  No. 1") to that certain Rights
Agreement  (the "Rights  Agreement")  by and between  Celsion  Corporation  (the
"Company")  and  American  Stock  Transfer & Trust  Company as Rights Agent (the
"Rights  Agent")  dated as of August 15,  2002,  is entered into the 16th day of
January,  2003.  Capitalized terms used herein, but not otherwise defined, shall
have the meanings ascribed thereto in the Rights Agreement.

         WHEREAS,  the Board of Directors of the Company has determined  that it
is  necessary  and  desirable  to amend  the  Rights  Agreement  to  provide  an
additional exclusion from the definition of an "Acquiring Person";

         WHEREAS,  pursuant to Section 27 of the Rights  Agreement,  the Company
may amend the Rights  Agreement  without  the  approval of any holders of Rights
Certificates  as the Company may deem necessary or desirable  until such time as
the Rights are no longer redeemable; and

         WHEREAS, the Rights are currently redeemable.

         NOW, THEREFORE,  in consideration of the foregoing and of the covenants
and agreements  contained  herein and in the Rights Agreement and other good and
valuable consideration, the Rights Agreement hereby is amended as follows:

         1.  Amendatory  Provision.   Pursuant  to  Section  27  of  the  Rights
Agreement, Section 1(a) of the Rights Agreement hereby is amended to provide the
following   additional   exclusion  to  the  definition  of  "Acquiring  Person"
subsequent to item (iii) of the first  sentence of that Section,  to be numbered
as item (iv) of the first sentence of that Section and to read as follows:

         (iv)  Boston  Scientific   Corporation  ("BSC")  shall  not  become  an
         "Acquiring Person" as the result of the acquisition of shares of Common
         Stock by BSC solely (a) pursuant to that certain Transaction Agreement,
         dated as of January 20,  2003,  by and between the Company and BSC (the
         "BSC  Transaction  Agreement") and (b) pursuant to a stock dividend on,
         subdivision of, or similar  proportionate  adjustment in (collectively,
         an  "Adjustment"),  the shares of Common Stock received pursuant to the
         BSC Transaction Agreement,  provided, however, that if BSC shall become
         the  Beneficial  Owner of an  aggregate of 15% or more of the shares of
         Common Stock then  outstanding  by reason of share  acquisitions  other
         than pursuant to the BSC Transaction  Agreement or an Adjustment in the
         shares  received  pursuant  thereto  (provided  that such aggregate may
         include shares of Common Stock acquired pursuant to the BSC Transaction
         Agreement  or any  Adjustment),  then  BSC  shall  be  deemed  to be an
         "Acquiring Person".
                                       1


         2.  Execution by the Rights  Agent.  Upon the delivery of a certificate
from an appropriate  officer of the Company which states that this Amendment No.
1 is compliance with the terms of Section 27 of the Rights Agreement, the Rights
Agent shall execute this Amendment No 1.

         3.  Effective  Time.  Notwithstanding  Section  2 hereof,  pursuant  to
Section 27 of the Rights Agreement,  this Amendment No. 1 shall become effective
immediately upon execution by the Company.

         4. Existing  Agreement.  Except as expressly amended hereby, all of the
terms,  covenants and  conditions  of the Rights  Agreement (i) are ratified and
confirmed;  (ii) shall remain unamended and not waived; and (iii) shall continue
in full force and effect.

         5. Governing Law. This Amendment No. 1 shall be deemed to be a contract
made  under  the laws of the State of  Delaware  and for all  purposes  shall be
governed by and construed in accordance  with the laws of such State  applicable
to contracts to be made and performed entirely within such State.

         6.  Severability.  If any term,  provision,  covenant or restriction of
this Amendment No. 1 or of the Rights  Agreement is held by a court of competent
jurisdiction  or other  authority  to be  invalid,  void or  unenforceable,  the
remainder of the terms, provisions, covenants and restrictions of this Amendment
No. 1 and the Rights  Agreement  shall remain in full force and effect and shall
in no way be affected, impaired or invalidated.

         7. Counterparts.  This Amendment No. 1 may be executed in counterparts,
each of which shall for all purposes be deemed to be an  original,  and all such
counterparts shall together constitute but one and the same instrument.

                            [SIGNATURE PAGE FOLLOWS]

                                       2



         IN WITNESS WHEREOF, Celsion Corporation has caused this Amendment No. 1
to be duly executed on the date first above written.


                 CELSION CORPORATION


                 By: /s/  Anthony P. Deasey
                     ----------------------------------------
                 Name:    Anthony P. Deasey
                 Title:   Executive Vice President - Finance
                          and Administration and Chief
                          Financial Officer


Executed by American Stock Transfer & Trust Company,  as Rights Agent,  this 6th
day of February, 2003.


- --------------------------------
AMERICAN STOCK TRANSFER & TRUST
COMPANY, as Rights Agent

By:   /s/Herbert J. Lemmer
      ---------------------
Name:    Herbert J. Lemmer
Title:   Vice President

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