Statement of Financial Position [Abstract] Finite-Lived Intangible Assets, Major Class Name [Domain] ASSETS ASSETS [Abstract] Current assets: Current assets: [Abstract] Cash and cash equivalents Investment securities – available for sale, at fair value Accrued interest receivable on investment securities Advances, deposits and other current assets Total current assets Property and equipment (at cost, less accumulated depreciation of $1,435,190 and $1,264,190, respectively) Other assets: Other assets: [Abstract] Finite lived intangible assets, net Goodwill Deposits, deferred fees and other assets Total other assets Total assets LIABILITIES AND STOCKHOLDERS' EQUITY LIABILITIES AND STOCKHOLDERS' EQUITY [Abstract] Current liabilities: Current liabilities: [Abstract] Accounts payable Accrued liabilities Notes payable – current portion Deferred revenue – current portion Total current liabilities Earnout milestone liability Carrying value as of the balance sheet date of common stock warrant liability. Common stock warrant liability Notes payable, net of discounts Deferred revenue Other non-current liabilities Total liabilities Stockholders' equity: Stockholders' equity: [Abstract] Preferred stock, $0.01 par value: 100,000 shares authorized; no shares issued or outstanding at June 30, 2014 and December 31, 2013, respectively Common stock, $0.01 par value; 75,000,000 shares authorized; 20,082,353 and 13,737,970 shares issued at June 30, 2014 and December 31, 2013, and 19,958,121 and 13,604,975 shares outstanding at June 30, 2014 and December 31, 2013, respectively Additional paid-in capital Accumulated other comprehensive loss Accumulated deficit Subtotal Treasury stock, at cost (124,232 and 132,995 shares at June 30, 2014 and December 31, 2013, respectively) Total stockholders' equity Total liabilities and stockholders' equity Accumulated depreciation (in Dollars) Preferred stock, par value (in Dollars per share) Preferred stock, shares authorized Preferred stock, shares issued Preferred stock, shares outstanding Common stock, par value (in Dollars per share) Common stock, shares authorized Common stock, shares issued Common stock, shares outstanding Treasury stock, shares Income Statement [Abstract] Licensing revenue Operating expenses: Operating expenses: [Abstract] Research and development General and administrative Acquisition costs Total operating expenses Loss from operations Other (expense) income: Other (expense) income: [Abstract] The amount recognized in earnings related to the change in fair value during the period of common stock warrant liability. (Loss) gain from change in valuation of common stock warrant liability Investment income, net Interest expense Other expense Total other (expense) income, net Net income (loss) Non-cash deemed dividend from beneficial conversion feature on convertible preferred stock Net (loss) income attributable to common shareholders Net income (loss) attributable to common shareholders per common share Net income (loss) attributable to common shareholders per common share [Abstract] Basic and diluted (in Dollars per share) Weighted average shares outstanding Weighted average shares outstanding [Abstract] Basic (in Shares) Diluted (in Shares) Statement of Comprehensive Income [Abstract] Other comprehensive (loss) gain Other comprehensive (loss) gain [Abstract] Changes in: Changes in: [Abstract] Realized loss on investment securities recognized in investment income, net Unrealized gain (loss) on investment securities Other comprehensive gain (loss) Net (loss) income Comprehensive (loss) income Statement of Cash Flows [Abstract] Major Types of Debt and Equity Securities [Domain] Business Acquisition, Acquiree [Domain] Cash flows from operating activities: Cash flows from operating activities: [Abstract] Net loss Non-cash items included in net loss: Non-cash items included in net loss: [Abstract] Depreciation and amortization The non-cash amount recognized in earnings related to the change in fair value during the period of common stock warrant liability. Change in fair value of common stock warrant liability Deferred revenue Stock-based compensation Treasury shares issued for services and 401(k) matching contributions Change in deferred rent liability Deferred finance charges. Amortization of deferred finance charges and debt discount associated with notes payable Loss on sale of investment securities Cash received for non-refundable research and development fee. Cash received for non-refundable technology transfer fee Net changes in: Net changes in: [Abstract] Accrued interest on short term investments and other current assets Accounts payable Accrued liabilities Net cash used in operating activities: Cash flows from investing activities: Cash flows from investing activities: [Abstract] Purchases of investment securities Proceeds from sale and maturity of investment securities Cash used in acquisition of EGEN, Inc. (net of cash received) The cash inflow from the refund of deposit for a letter of credit. Refund of deposit for letter of credit Purchases of property and equipment Net cash used in investing activities Cash flows from financing activities: Cash flows from financing activities: [Abstract] Proceeds from sale of common stock equity, net of issuance costs Proceeds from sale of preferred stock, net of issuance costs Proceeds from exercise of common stock warrants Proceeds from exercise of options to purchase common stock Proceeds from note payable Principal payments on notes payable Net cash provided by financing activities Increase (decrease) in cash and cash equivalents Cash and cash equivalents at beginning of period Cash and cash equivalents at end of period Supplemental disclosures of cash flow information: Supplemental disclosures of cash flow information: [Abstract] Interest paid Fair value of common stock issued in acquisition of Egen, Inc. assets Disclosure Text Block [Abstract] Nature of Operations [Text Block] Basis of Presentation and Significant Accounting Policies [Text Block] Description of New Accounting Pronouncements Not yet Adopted [Text Block] Earnings Per Share [Abstract] Earnings Per Share [Text Block] Investments, Debt and Equity Securities [Abstract] Investments in Debt and Marketable Equity Securities (and Certain Trading Assets) Disclosure [Text Block] Fair Value Disclosures [Abstract] Fair Value Disclosures [Text Block] Business Combinations [Abstract] Business Combination Disclosure [Text Block] Goodwill and Intangible Assets Disclosure [Abstract] Goodwill and Intangible Assets Disclosure [Text Block] Payables and Accruals [Abstract] Accounts Payable and Accrued Liabilities Disclosure [Text Block] Debt Disclosure [Abstract] Debt Disclosure [Text Block] Stockholders' Equity Note [Abstract] Stockholders' Equity Note Disclosure [Text Block] Disclosure of Compensation Related Costs, Share-based Payments [Abstract] Disclosure of Compensation Related Costs, Share-based Payments [Text Block] Warrants [Abstract] Warrants [Abstract] The entire disclosure for warrant liabilities. Warrants [Text Block] Commitments and Contingencies Disclosure [Abstract] Commitments and Contingencies Disclosure [Text Block] Licensing Transaction [Abstract] Licensing Transaction [Abstract] The entire disclosure for a contractual arrangement, in which the Company gave another party an exclusive license. Licensing Transaction [Text Block] Available-for-sale Securities [Table Text Block] Schedule of Unrealized Loss on Investments [Table Text Block] Investment Income [Table Text Block] Schedule of Accumulated Other Comprehensive Income (Loss) [Table Text Block] Schedule of Fair Value, Assets and Liabilities Measured on Recurring Basis [Table Text Block] Schedule of Business Acquisitions by Acquisition, Contingent Consideration [Table Text Block] Schedule of Recognized Identified Assets Acquired and Liabilities Assumed [Table Text Block] Business Acquisition, Pro Forma Information [Table Text Block] Schedule of Intangible Assets and Goodwill [Table Text Block] Schedule of Accrued Liabilities [Table Text Block] Schedule of Maturities of Long-term Debt [Table Text Block] Plan Name [Domain] Note 11 - Stockholders' Equity (Tables) [Table] Note 11 - Stockholders' Equity (Tables) [Line Items] Schedule of Share-based Payment Award, Stock Options, Valuation Assumptions [Table Text Block] Schedule of Share-based Payment Award, Employee Stock Purchase Plan, Valuation Assumptions [Table Text Block] Schedule of Shar-based Compensation, Stock Options and Restricted Stock Awards, Activity [Table Text Block] Equity Award [Domain] Note 13 - Warrants (Tables) [Table] Note 13 - Warrants (Tables) [Line Items] Schedule of Share-based Compensation, Stock Options, Activity [Table Text Block] Schedule of Common Stock Warrant Liability Valuation Assumptions [Table Text Block] Schedule of Common Stock Warranty Liability [Table Text Block] Schedule of Stockholders' Equity Note, Warrants or Rights [Table Text Block] Short-Term Investment by Bond Maturities Short-Term Investment by Bond Maturities [Abstract] Schedule of Available-for-sale Securities [Table] Schedule of Available-for-sale Securities [Line Items] Corporate bond maturities Corporate bond maturities [Abstract] Cost Fair value Investment Securities Gross Unrealized Losses and Fair Value by Investment Category Investment Securities Gross Unrealized Losses and Fair Value by Investment Category [Abstract] Note 5 - Investment Securities - Available For Sale (Details) - Investment Securities Gross Unrealized Losses and Fair Value by Investment Category [Table] Note 5 - Investment Securities - Available For Sale (Details) - Investment Securities Gross Unrealized Losses and Fair Value by Investment Category [Line Items] Available for Sale (all unrealized holding gains and losses are less than 12 months at date of measurement) Available for Sale (all unrealized holding gains and losses are less than 12 months at date of measurement) [Abstract] Available for sale securities with continuous gain position less than 12 months fair value. Bonds – corporate issuances with unrealized gains