001 - Statement - Condensed Consolidated Balance Sheets (Current Period Unaudited) link:presentationLink link:definitionLink link:calculationLink 002 - Statement - Condensed Consolidated Balance Sheets (Current Period Unaudited) (Parentheticals) link:presentationLink link:definitionLink link:calculationLink 003 - Statement - Condensed Consolidated Statements of Operations (Unaudited) link:presentationLink link:definitionLink link:calculationLink 004 - Statement - Condensed Consolidated Statements of Comprehensive (Loss) (Unaudited) link:presentationLink link:definitionLink link:calculationLink 005 - Statement - Condensed Consolidated Statements of Cash Flows (Unaudited) link:presentationLink link:definitionLink link:calculationLink 006 - Disclosure - Note 1 - Business Description link:presentationLink link:definitionLink link:calculationLink 007 - Disclosure - Note 2 - Basis of Presentation link:presentationLink link:definitionLink link:calculationLink 008 - Disclosure - Note 3 - New Accounting Pronouncements link:presentationLink link:definitionLink link:calculationLink 009 - Disclosure - Note 4 - Net Loss per Common Share link:presentationLink link:definitionLink link:calculationLink 010 - Disclosure - Note 5 - Investment Securities - Available for Sale link:presentationLink link:definitionLink link:calculationLink 011 - Disclosure - Note 6 - Fair Value of Measurements link:presentationLink link:definitionLink link:calculationLink 012 - Disclosure - Note 7 - Acquisition of EGEN, Inc. link:presentationLink link:definitionLink link:calculationLink 013 - Disclosure - Note 8 - Accrued Liabilities link:presentationLink link:definitionLink link:calculationLink 014 - Disclosure - Note 9 - Note Payable link:presentationLink link:definitionLink link:calculationLink 015 - Disclosure - Note 10 - Stockholders' Equity link:presentationLink link:definitionLink link:calculationLink 016 - Disclosure - Note 11 - Stock Based Compensation link:presentationLink link:definitionLink link:calculationLink 017 - Disclosure - Note 12 - Earn-Out Milestone Liability link:presentationLink link:definitionLink link:calculationLink 018 - Disclosure - Note 13 - Warrants link:presentationLink link:definitionLink link:calculationLink 019 - Disclosure - Note 14 - Contingent Liabilities and Commitments link:presentationLink link:definitionLink link:calculationLink 020 - Disclosure - Note 15 - Technology Development and Licensing Agreements link:presentationLink link:definitionLink link:calculationLink 021 - Disclosure - Note 5 - Investment Securities - Available for Sale (Tables) link:presentationLink link:definitionLink link:calculationLink 022 - Disclosure - Note 6 - Fair Value of Measurements (Tables) link:presentationLink link:definitionLink link:calculationLink 023 - Disclosure - Note 7 - Acquisition of EGEN, Inc. (Tables) link:presentationLink link:definitionLink link:calculationLink 024 - Disclosure - Note 8 - Accrued Liabilities (Tables) link:presentationLink link:definitionLink link:calculationLink 025 - Disclosure - Note 9 - Note Payable (Tables) link:presentationLink link:definitionLink link:calculationLink 026 - Disclosure - Note 11 - Stock Based Compensation (Tables) link:presentationLink link:definitionLink link:calculationLink 027 - Disclosure - Note 12 - Earn-Out Milestone Liability (Tables) link:presentationLink link:definitionLink link:calculationLink 028 - Disclosure - Note 13 - Warrants (Tables) link:presentationLink link:definitionLink link:calculationLink 029 - Disclosure - Note 4 - Net Loss per Common Share (Details) link:presentationLink link:definitionLink link:calculationLink 030 - Disclosure - Note 5 - Investment Securities - Available for Sale (Details) link:presentationLink link:definitionLink link:calculationLink 031 - Disclosure - Note 5 - Investment Securities - Available for Sale (Details) - Short-Term Investment by Bond Maturities link:presentationLink link:definitionLink link:calculationLink 032 - Disclosure - Note 5 - Investment Securities - Available for Sale (Details) - Investment Securities Gross Unrealized Losses and Fair Value by Investment Category link:presentationLink link:definitionLink link:calculationLink 033 - Disclosure - Note 5 - Investment Securities - Available for Sale (Details) - Investment Income link:presentationLink link:definitionLink link:calculationLink 034 - Disclosure - Note 5 - Investment Securities - Available for Sale (Details) - Component of Accumulated Other Comprehensive Loss link:presentationLink link:definitionLink link:calculationLink 035 - Disclosure - Note 6 - Fair Value of Measurements (Details) - Assets and Liabilities at Fair Value on a Recurring Basis link:presentationLink link:definitionLink link:calculationLink 036 - Disclosure - Note 7 - Acquisition of EGEN, Inc. 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(Details) - Pro Forma Information link:presentationLink link:definitionLink link:calculationLink 041 - Disclosure - Note 8 - Accrued Liabilities (Details) - Accrued Liabilities link:presentationLink link:definitionLink link:calculationLink 042 - Disclosure - Note 9 - Note Payable (Details) link:presentationLink link:definitionLink link:calculationLink 043 - Disclosure - Note 9 - Note Payable (Details) - Future Principal Payments Due on the Credit Agreement link:presentationLink link:definitionLink link:calculationLink 044 - Disclosure - Note 10 - Stockholders' Equity (Details) link:presentationLink link:definitionLink link:calculationLink 045 - Disclosure - Note 11 - Stock Based Compensation (Details) link:presentationLink link:definitionLink link:calculationLink 046 - Disclosure - Note 11 - Stock Based Compensation (Details) - Fair Value of Option Assumptions link:presentationLink link:definitionLink link:calculationLink 047 - Disclosure - Note 11 - Stock Based Compensation (Details) - Stock Option and Restricted Stock Awards link:presentationLink link:definitionLink link:calculationLink 048 - Disclosure - Note 12 - Earn-Out Milestone Liability (Details) link:presentationLink link:definitionLink link:calculationLink 049 - Disclosure - Note 12 - Earn-Out Milestone Liability (Details) - Summary of the Changes in the Earn-Out Milestone Liability link:presentationLink link:definitionLink link:calculationLink 050 - Disclosure - Note 13 - Warrants (Details) link:presentationLink link:definitionLink link:calculationLink 051 - Disclosure - Note 13 - Warrants (Details) - Summary of Warrant Activity link:presentationLink link:definitionLink link:calculationLink 052 - Disclosure - Note 13 - Warrants (Details) - Fair Value of Warrants Assumptions link:presentationLink link:definitionLink link:calculationLink 053 - Disclosure - Note 13 - Warrants (Details) - Common Stock Warrant Liability link:presentationLink link:definitionLink link:calculationLink 054 - Disclosure - Note 14 - Contingent Liabilities and Commitments (Details) link:presentationLink link:definitionLink link:calculationLink 055 - Disclosure - Note 15 - Technology Development and Licensing Agreements (Details) link:presentationLink link:definitionLink link:calculationLink 000 - Disclosure - Document And Entity Information link:presentationLink link:definitionLink link:calculationLink