Equity Components [Axis]
Preferred Stock [Member]
Class of Stock [Axis]
Series A and B Preferred Stock [Member]
Common Stock [Member]
Additional Paid-in Capital [Member]
Treasury Stock, Common [Member]
AOCI Attributable to Parent [Member]
Retained Earnings [Member]
Geographical [Axis]
NEW JERSEY
Lender Name [Axis]
Silicon Valley Bank [Member]
Financial Instrument [Axis]
US Treasury Securities [Member]
Corporate Debt Securities [Member]
Measurement Frequency [Axis]
Fair Value, Recurring [Member]
Fair Value Hierarchy and NAV [Axis]
Fair Value, Inputs, Level 1 [Member]
Fair Value, Inputs, Level 2 [Member]
Fair Value, Inputs, Level 3 [Member]
Business Acquisition [Axis]
EGEN Inc [Member]
Legal Entity [Axis]
IPR and D Drug Technology Platforms [Member]
Finite-Lived Intangible Assets by Major Class [Axis]
In Process Research and Development [Member]
Statistical Measurement [Axis]
Maximum [Member]
Minimum [Member]
Collaborative Arrangement and Arrangement Other than Collaborative [Axis]
Market Offering Agreement [Member]
Series A Convertible Redeemable Preferred Stock [Member]
Series B Convertible Redeemable Preferred Stock [Member]
Series A & B Preferred [Member]
Securities Purchase Agreement [Member]
Sale of Stock [Axis]
April 2022 Registered Direct Offering [Member]
Plan Name [Axis]
2018 Stock Incentive Plan [Member]
2007 Stock Incentive Plan [Member]
Inducement Option Grants [Member]
Title of Individual [Axis]
Ten New Employees [Member]
Award Type [Axis]
Restricted Stock [Member]
Inducement Awards [Member]
Equity Stock Awards [Member]
Scenario [Axis]
Granted Under 2018 Plan and 2007 Plan [Member]
Stock Options and Restricted Stock Awards [Member]
Income Statement Location [Axis]
Research and Development Expense [Member]
General and Administrative Expense [Member]
Share-Based Payment Arrangement, Option [Member]
Amended Asset Purchase Agreement [Member]
Related Party Transaction [Axis]
Within One Year of Achieving Milestone [Member]
EGWC, Inc [Member]
10 Business Days of Achieving Milestone [Member]
1st Lease Amendment [Member]
Second Lease Amendment [Member]
First Year [Member]
Final Year [Member]
Lease Agreement [Member]
Legal Entity of Counterparty, Type [Axis]
Hisun [Member]
Convertible Note Purchase Agreement [Member]
Transomic Technologies Inc [Member]
Subsequent Event Type [Axis]
Subsequent Event [Member]
Cover [Abstract]
Document Type
Amendment Flag
Amendment Description
Document Registration Statement
Document Annual Report
Document Quarterly Report
Document Transition Report
Document Shell Company Report
Document Shell Company Event Date
Document Period Start Date
Document Period End Date
Document Fiscal Period Focus
Document Fiscal Year Focus
Current Fiscal Year End Date
Entity File Number
Entity Registrant Name
Entity Central Index Key
Entity Primary SIC Number
Entity Tax Identification Number
Entity Incorporation, State or Country Code
Entity Address, Address Line One
Entity Address, Address Line Two
Entity Address, Address Line Three
Entity Address, City or Town
Entity Address, State or Province
Entity Address, Country
Entity Address, Postal Zip Code
Country Region
City Area Code
Local Phone Number
Extension
Written Communications
Soliciting Material
Pre-commencement Tender Offer
Pre-commencement Issuer Tender Offer
Title of 12(b) Security
No Trading Symbol Flag
Trading Symbol
Security Exchange Name
Title of 12(g) Security
Security Reporting Obligation
Annual Information Form
Audited Annual Financial Statements
Entity Well-known Seasoned Issuer
Entity Voluntary Filers
Entity Current Reporting Status
Entity Interactive Data Current
Entity Filer Category
Entity Small Business
Entity Emerging Growth Company
Elected Not To Use the Extended Transition Period
Document Accounting Standard
Other Reporting Standard Item Number
Entity Shell Company
Entity Public Float
Entity Bankruptcy Proceedings, Reporting Current
Entity Common Stock, Shares Outstanding
Documents Incorporated by Reference [Text Block]
Entity Information, Former Legal or Registered Name
Statement of Financial Position [Abstract]
ASSETS
Current assets:
Cash and cash equivalents
Investment in debt securities - available for sale, at fair value
Accrued interest receivable on investment securities
Money market investments, restricted cash
Advances and deposits on clinical programs and other current assets
Total current assets
Property and equipment (at cost, less accumulated depreciation and amortization)
Other assets:
Money market investments, restricted cash
Deferred income tax asset
Operating lease right-of-use assets, net
Deposits and other assets
Total other assets
Total assets
LIABILITIES AND STOCKHOLDERS’ EQUITY
Current liabilities:
Accounts payable – trade
Other accrued liabilities
Note payable – current portion, net of deferred financing costs
Operating lease liability - current portion
Total current liabilities
Notes payable – non-current portion, net of deferred financing costs
Operating lease liability - non-current portion
Total liabilities
Commitments and contingencies
Stockholders’ equity:
Preferred stock - $0.01 par value (100,000 shares authorized, and no shares issued or outstanding at March 31, 2023 and December 31, 2022)
Common stock - $0.01 par value (112,500,000 shares authorized; 9,097,027 and 7,436,219 shares issued at March 31, 2023 and December 31, 2022, respectively; and 9,097,005 and 7,436,197 shares outstanding at March 31, 2023 and December 31, 2022, respectively)
Additional paid-in capital
Accumulated other comprehensive loss
Accumulated deficit
Total stockholders’ equity before treasury stock
Treasury stock, at cost (22 shares at March 31, 2023 and December 31, 2022)
Total stockholders’ equity
Total liabilities and stockholders’ equity
Preferred stock, par value
Preferred stock, shares authorized
Preferred stock, shares issued
Preferred stock, shares outstanding
Common stock, par value
Common stock, shares authorized
Common stock, shares issued
Common stock, shares outstanding
Treasury stock, shares
Income Statement [Abstract]
Licensing revenue
Operating expenses:
Research and development
General and administrative
Total operating expenses
Loss from operations
Other (expense) income:
Investment income
Interest expense on preferred stock
Interest expense on loan facility
Other income
Total other income (expense), net
Net loss
Net loss per common share
Basic and diluted
Weighted average shares outstanding
Basic and diluted
Statement of Comprehensive Income [Abstract]
Other comprehensive loss
Changes in:
Realized gains on debt securities recognized in investment income, net
Unrealized losses on debt securities, net
Change in realized and unrealized gains (losses) on available for sale securities, net
Net loss
Total Comprehensive loss
Statement of Cash Flows [Abstract]
Cash flows from operating activities:
Adjustments to reconcile net loss to net cash used in operating activities:
Depreciation and amortization
Recognition of deferred revenue
Stock-based compensation
Realization of deferred income tax asset
Amortization of deferred finance charges and debt discount associated with notes payable
Net changes in:
Accrued interest on investment securities
Advances, deposits, and other current assets
Accounts payable and accrued liabilities
Net cash used in operating activities
Cash flows from investing activities:
Purchases of investment securities
Proceeds from sale and maturity of investment securities
Purchases of property and equipment
Net cash provided by investing activities
Cash flows from financing activities:
Proceeds from redeemable convertible preferred stock offering
Payment upon redemption of redeemable convertible preferred stock
Proceeds from sale of common stock equity, net of issuance costs
Net cash provided by financing activities
Net change in cash, cash equivalents and restricted cash
Cash, cash equivalents and restricted cash at beginning of period
Cash, cash equivalents and restricted cash at end of period
Supplemental disclosures of cash flow information:
Interest paid
Recognition of Right Use Asset and Liability
Cash paid for amounts included in measurement of lease liabilities:
Operating cash flows for lease payments
Realized and unrealized gains (losses), net, on investment securities
Statement [Table]
Statement [Line Items]
Beginning balance, value
Beginning Balance, shares
Sale of equity through equity financing facilities, net of costs
Sale of equity through equity financing facilities, net of costs, shares
Issuance of common stock for restricted options
Issuance of common stock for restricted options, shares
Realized and unrealized gains and losses, net, on investment securities
Stock-based compensation expense
Effect of reverse stock split
Effect of reverse stock split, shares
Issuance of preferred stock upon financing
Issuance of preferred stock upon financing, shares
Redemption of preferred stock
Redemption of preferred stock, shares
Ending balance, value
Ending Balance, shares
Accounting Policies [Abstract]
Business Description
Organization, Consolidation and Presentation of Financial Statements [Abstract]
Basis of Presentation
Accounting Changes and Error Corrections [Abstract]
New Accounting Pronouncements
Receivables [Abstract]
Restricted Cash
Earnings Per Share [Abstract]
Net Loss per Common Share
Investments, Debt and Equity Securities [Abstract]
Investment in Debt Securities-Available for Sale
Fair Value Measurements
Fair Value Measurements
Goodwill and Intangible Assets Disclosure [Abstract]
Intangible Assets
Payables and Accruals [Abstract]
Accrued Liabilities
Debt Disclosure [Abstract]
Notes Payable
Equity [Abstract]
Stockholders’ Equity
Share-Based Payment Arrangement [Abstract]
Stock-Based Compensation
Earn-out Milestone Liability
Earn-Out Milestone Liability
Warrants
Warrants
Leases
Leases
Technology Development And Licensing Agreements
Technology Development and Licensing Agreements
Commitments and Contingencies Disclosure [Abstract]
Commitments and Contingencies
Related Party Transactions [Abstract]
Related Party Transaction
Subsequent Events [Abstract]
Subsequent Events
Schedule of Cash and Cash Equivalents and Restricted Cash
Schedule of Cost, Fair Value and Maturities of Short Term Investments
Summary of Investment Securities Gross Unrealized Gains (Losses)
Summary of Net Realized Losses On Sales of Available for Sale Securities and Investment Income Interest and Dividends
Schedule of Fair Value, Assets and Liabilities Measured On Recurring Basis
Schedule of Other Accrued Liabilities
Schedule of Future Principal Payments, Net of Unamortized Debt Discounts
Summary of Stock Options Awards and Restricted Stock Grants
Schedule of Assumptions Used to Determine Fair Value of Options Granted
Summary of Warrant Activity
Schedule of Lease Payments and Maturity of Operating Lease Liabilities
Cash and cash equivalents, short-term investments
Restricted cash
Operating losses
Money market investments, restricted cash
Total
Line of Credit Facility [Table]
Line of Credit Facility [Line Items]
Restricted investments
Anti-dilutive securities
Marketable Securities [Table]
Marketable Securities [Line Items]
Short-term investments - Cost
Short-term investments - Fair Value
Short-term investment maturities - Within 3 months, cost
Short-term investment maturities - Within 3 months, fair value
Short-term investment maturities - Between 3-12 months, cost
Short-term investment maturities - Between 3-12 months, fair value
Total, cost
Total, fair value
Investments with unrealized gains, Fair Value
Investments with unrealized gains, Unrealized Holding Gains (Losses)
Investments with unrealized losses, Fair Value
Investments with unrealized Losses, Unrealized Holding Gains (Losses)
Total, Fair Value
Total, Unrealized Holding Gains (Losses)
Interest and dividends accrued and paid
Realized gains (losses)
Investment income, net
Fair Value, Recurring and Nonrecurring [Table]
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]
Schedule of Finite-Lived Intangible Assets [Table]
Finite-Lived Intangible Assets [Line Items]
Estimated acquisition price
Asset impairment charges
Non-cash charge
Amounts due to contract research organizations and other contractual agreements
Accrued payroll and related benefits
Accrued interest
Accrued professional fees
Other
Total
2023
2024
2025
2026 and thereafter
Subtotal of future principal payments
Amortized end-of term fee, net
Total
Line of credit facility, maximum borrowing capacity
Proceeds from lines of credit
Debt instrument, interest rate
Final payment percentage
Long term line of credit
Debt instrument, description
Financing fees and expenses
End of term charge percentage
Interest expense
Interest expense, debt
Amortization of debt issuance costs
Accumulated Other Comprehensive Income (Loss) [Table]
Accumulated Other Comprehensive Income (Loss) [Line Items]
Reverse stock split, description
Reverse stock split common stock outstanding
Warrants issued
Stock issued during period, value, new issues
Number of shares sold
Proceeds from sale of stock
Preferred stock, stated value
Share price
OriginalIssueDiscountRate
Proceeds from issuance of preferred stock
Preferred stock, conversion price
Conversion of stock, shares issued
Preferred stock, voting rights
Redemption term description
Proceeds from issuance under placement
Shares issued, redemption value
Legal fees
Stock issued, shares
Proceeds from issuance of common stock
Placement agent fee description
Schedule of Share-Based Compensation Arrangements by Share-Based Payment Award [Table]
Share-Based Compensation Arrangement by Share-Based Payment Award [Line Items]
Options outstanding, beginning balance
Weighted average exercise price, beginning balance
Non-vested stock awards, beginning balance
Weighted average grant date fair value, beginning balance
Options outstanding, granted
Weighted average exercise price, granted
Non-vested stock awards, granted
Weighted average grant date fair value, granted
Options outstanding, vested and issued
Weighted average exercise price, vested and issued
Non-vested stock awards, vested and issued
Weighted average grant date fair value, vested and issued
Options outstanding, Terminated
Weighted average exercise price, Terminated
Non-vested stock awards, Terminated
Weighted average grant date fair value, Terminated
Options outstanding, ending balance
Weighted average exercise price, ending balance
Non-vested stock awards, ending balance
Weighted average grant date fair value, ending balance
Weighted average contractual terms
Options outstanding, aggregate intrinsic value
Non-vested stock awards, aggregate intrinsic value
Options outstanding, exercisable
Weighted average exercise price, exercisable
Weighted average contractual terms, exercisable
Options outstanding, aggregate intrinsic value, exercisable
Risk-free interest rate
Expected volatility, minimum
Expected volatility, maximum
Expected volatility
Expected life (in years)
Expected dividend yield
Share-based payment award, shares authorized
Shares available for issuance
Stock options, strike price description
Shares issued, shares
Options granted, weighted average exercise price
Common stock, outstanding
Common stock, reserved for future issuance
Share based compensation
Unrecognized share based compensation
Unrecognized share based compensation, period
Collaborative Arrangement and Arrangement Other than Collaborative [Table]
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Earnout milestone liability
Earnout payment options description
Non-cash charge on earnout milestone liability
Summary Of Warrant Activity
Number of Warrants Issued, Warrants outstanding, Beginning balance
Weighted Average Exercise Price, Warrants outstanding, Beginning balance
Number of Warrants Issued, warrants expired
Weighted Average Exercise Price, Warrants expired
Number of Warrants Issued, Warrants outstanding, Ending balance
Weighted Average Exercise Price, Warrants outstanding, Ending balance
Aggregate intrinsic value of outstanding warrants
Weighted average remaining contractual terms (years)
Schedule Of Lease Payments And Maturity Of Operating Lease Liabilities
2023
2024
2025
2026
and thereafter
Subtotal future lease payments
Less imputed interest
Total lease liabilities
Operating lease, weighted average remaining lease term
Operating lease, weighted average discount rate, percent
Lease operating, description
Area of land
Operating lease, term
Payments for rent
Operating lease, cost
Operating lease, payments
Schedule of Accounts, Notes, Loans and Financing Receivable [Table]
Accounts, Notes, Loans and Financing Receivable [Line Items]
Proceeds from license fees received
Deferred revenue
Deferred revenue amortization period
Legal Fees
Convertable and warrants
Interest rate, percentage
Subsequent Event [Table]
Subsequent Event [Line Items]
Repaid loan payment
Collateral account
Silicon Valley Bank [Member]
Amortized cost of investment in debt security measured at fair value with change in fair value recognized in other comprehensive income (available-for-sale) with single maturity date and allocated without single maturity date, maturing in next rolling three months.
Amortized cost of investment in debt security measured at fair value with change in fair value recognized in other comprehensive income (available-for-sale), with single maturity date and allocated without single maturity date, maturing in next rolling three to twelve months.
The current amount of amortized cost of investment in debt security measured at fair value with change in fair value recognized in other comprehensive income (available-for-sale).
Fair value of investment in debt security measured at fair value with change in fair value recognized in other comprehensive income (available-for-sale), with single maturity date and allocated without single maturity date, maturing in next rolling three months.
Fair value of investment in debt security measured at fair value with change in fair value recognized in other comprehensive income (available-for-sale), with single maturity date and allocated without single maturity date, maturing in next rolling three to twelve months.
Available for sale securities unrealized gains fair value.
Available for sale securities unrealized losses fair value.
Available for sale securities unrealized gains less than twelve months.
Available for sale securities unrealized losses less than twelve months.
Available for sale securities unrealized gains (losses) less than twelve months.
Investment income loss non operating.
Interest expense on preferred stock
EGEN Inc [Member]
IPR and D Drug Technology Platforms [Member]
Non-cash charge.
Final Payment Percentage.
End of term charge percentage.
Amortization of deferred finance charges and debt discount associated with notes payable.
Realizedand unrealized gains and losses net on investment in debt securities.
Market Offering Agreement [Member]
Series A Convertible Redeemable Preferred Stock [Member]
Series B Convertible Redeemable Preferred Stock [Member]
Original issue discount rate.
Series A and B Preferred Stock [Member]
Stock issued during period value reverse stock splits.
Issuance of preferred stock upon financing.
Series A & B Preferred [Member]
Securities Purchase Agreement [Member]
April 2022 Registered Direct Offering [Member]
Placement agent fee description.
2018 Stock Incentive Plan [Member]
Stock options, strike price description.
2007 Stock Incentive Plan [Member]
Inducement Option Grants [Member]
Issuance of preferred stock upon financing, shares.
Inducement Awards [Member]
Equity Stock Awards [Member]
Granted Under 2018 Plan and 2007 Plan [Member]
Stock Options and Restricted Stock Awards [Member]
Operating lease liability payments due after year one and there after.
1st Lease Amendment [Member]
First Year [Member]
Final Year [Member]
Earnout Milestone Liability Disclosure [Text Block]
Earn-out payment options, description.
EGWC, Inc [Member]
Earnout milestone liability.
Amended Asset Purchase Agreement [Member]
Within One Year of Achieving Milestone [Member]
10 Business Days of Achieving Milestone [Member]
Non-cash charge on earnout milestone liability.
Disclosure of warrants.
Second Lease Amendment [Member]
Weighted average price at which grantees can acquire the shares reserved for issuance under the stock non-option equity plan.
Sharebased compensation arrangement by sharebased payment award non options outstanding intrinsic value.
Weighted average remaining contractual term for non-option awards outstanding, in 'PnYnMnDTnHnMnS' format, for example, 'P1Y5M13D' represents the reported fact of one year, five months, and thirteen days.
Lease Agreement [Member]
Disclosure of licensing transaction.
Hisun [Member]
The amortization period for deferred revenue.
Convertible Note Purchase Agreement [Member]
Transomic Technologies Inc [Member]
Summary of Stock Option and Restricted Stock Awards [Table Text Block]
Long-term debt maturities repayments of principal year two and there-after.
Share based compensation arrangement by share based payment award options vested and issued in period.
Share based compensation arrangement by share based payment award options vested and issued in period weighted average exercise price.
Ten New Employees [Member]
Debt instrument amortized fee net.
Recognition of right use asset and liability.
Assets, Current
Other Long-Term Investments
Other Assets, Noncurrent
Assets
Liabilities, Current
Liabilities
Stockholders' Equity before Treasury Stock
Treasury Stock, Value
Equity, Attributable to Parent
Liabilities and Equity
Operating Expenses
Operating Income (Loss)
InterestExpenseOnPreferredStock
Nonoperating Income (Expense)
Weighted Average Number of Shares Outstanding, Basic
Other Comprehensive Income (Loss), Reclassification Adjustment from AOCI for Sale of Securities, Net of Tax
OCI, Debt Securities, Available-for-Sale, Gain (Loss), after Adjustment and Tax
Comprehensive Income (Loss), Net of Tax, Attributable to Parent
Contract with Customer, Liability, Revenue Recognized
Increase (Decrease) in Accrued Investment Income Receivable
Increase (Decrease) in Other Current Assets
Net Cash Provided by (Used in) Operating Activities
Payments to Acquire Debt Securities, Available-for-Sale
Payments to Acquire Property, Plant, and Equipment
Net Cash Provided by (Used in) Investing Activities
Payments for Repurchase of Redeemable Convertible Preferred Stock
Net Cash Provided by (Used in) Financing Activities
Cash, Cash Equivalents, Restricted Cash, and Restricted Cash Equivalents, Period Increase (Decrease), Including Exchange Rate Effect
Cash, Cash Equivalents, Restricted Cash, and Restricted Cash Equivalents, Including Disposal Group and Discontinued Operations
Interest Paid, Excluding Capitalized Interest, Operating Activities
Shares, Outstanding
Stock Issued During Period, Shares, Reverse Stock Splits
Stock Redeemed or Called During Period, Shares
Derivatives and Fair Value [Text Block]
WarrantsTextBlock
Lessee, Operating Leases [Text Block]
Cash, Cash Equivalents, Restricted Cash, and Restricted Cash Equivalents
InvestmentIncomeLossNonoperating
Long-Term Debt, Gross
DebtInstrumentAmortizedFeeNet
Long-Term Debt
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding, Number
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding, Weighted Average Exercise Price
Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Nonvested, Number
Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Nonvested, Weighted Average Grant Date Fair Value
Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Vested in Period
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Forfeitures in Period
Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Forfeited in Period
Share-Based Compensation Arrangement by Share-Based Payment Award, Non-Option Equity Instruments, Outstanding, Number
ShareBasedCompensationArrangementByShareBasedPaymentAwardNonOptionEquityInstrumentsOutstandingWeightedAverageExercisePrice
Share-Based Compensation Arrangement by Share-Based Payment Award, Non-Option Equity Instruments, Expirations
Lessee, Operating Lease, Liability, to be Paid, Remainder of Fiscal Year
Lessee, Operating Lease, Liability, to be Paid, Year One
Lessee, Operating Lease, Liability, to be Paid, Year Two
Lessee, Operating Lease, Liability, to be Paid
Lessee, Operating Lease, Liability, Undiscounted Excess Amount