Date Filer Title Filing Type Shares Traded Price Total Held
March 23, 2011 CMO Form 4 Conversion of derivative security 6 -- --
March 23, 2011 CFO Form 4 Conversion of derivative security 8 -- --
March 23, 2011 Director Form 4 Conversion of derivative security 12 -- --
March 23, 2011 Director Form 4 Conversion of derivative security 83 -- --
March 23, 2011 CEO Form 4 Conversion of derivative security 41 -- --
March 23, 2011 Controller & CAO Form 4 Conversion of derivative security 8 -- --
January 8, 2010 Interim Chief Accnt Officer Form 3 Initial Statement of Beneficial Ownership of Securities -- -- --
January 8, 2010 Interim Chief Accnt Officer Form 3 Initial Statement of Beneficial Ownership of Securities -- -- --
January 8, 2010 Interim Chief Accnt Officer Form 3 Initial Statement of Beneficial Ownership of Securities -- -- --
June 17, 2008 VP & Chief Medical Officer Form 3 Initial Statement of Beneficial Ownership of Securities -- -- --
June 17, 2008 VP & Chief Medical Officer Form 3 Initial Statement of Beneficial Ownership of Securities -- -- --
June 17, 2008 VP & Chief Medical Officer Form 3 Initial Statement of Beneficial Ownership of Securities -- -- --
June 17, 2008 VP & Chief Medical Officer Form 3 Initial Statement of Beneficial Ownership of Securities -- -- --
June 17, 2008 VP & Chief Medical Officer Form 3 Initial Statement of Beneficial Ownership of Securities -- -- --
June 17, 2008 VP & Chief Medical Officer Form 3 Initial Statement of Beneficial Ownership of Securities -- -- --
June 17, 2008 VP & Chief Medical Officer Form 3 Initial Statement of Beneficial Ownership of Securities -- -- --
November 21, 2007 Chief Accounting Officer Form 3 Initial Statement of Beneficial Ownership of Securities -- -- --
November 21, 2007 Chief Accounting Officer Form 3 Initial Statement of Beneficial Ownership of Securities -- -- --
November 21, 2007 Chief Accounting Officer Form 3 Initial Statement of Beneficial Ownership of Securities -- -- --
March 14, 2007 Director Form 3 Initial Statement of Beneficial Ownership of Securities -- -- --
March 4, 2005 VP of Operations Form 3 Initial Statement of Beneficial Ownership of Securities -- -- --
March 4, 2005 VP of Operations Form 3 Initial Statement of Beneficial Ownership of Securities -- -- --
February 24, 2005 VP of Regulatory Affairs Form 3 Initial Statement of Beneficial Ownership of Securities -- -- --
February 24, 2005 VP of Regulatory Affairs Form 3 Initial Statement of Beneficial Ownership of Securities -- -- --
December 22, 2003 Director Form 4 Grant, award or other acquisition pursuant to Rule 16b-3(d) 41,287 -- --

For recent transactions, including derivative transactions, see our Section 16 SEC filings page.

* Represents the number of non-derivative securities directly held. (I) Indicates that some (or all) of these shares are held indirectly.