Date Filer Title Filing Type Shares Traded Price Total Held
May 14, 2019 Director Form 4 Grant, award or other acquisition pursuant to Rule 16b-3(d) 10,000 -- 87,357
February 19, 2019 CMO Form 4 Grant, award or other acquisition pursuant to Rule 16b-3(d) 20,000 -- 325,047
February 19, 2019 Director Form 4 Grant, award or other acquisition pursuant to Rule 16b-3(d) 12,000 -- 77,357
February 19, 2019 Director Form 4 Grant, award or other acquisition pursuant to Rule 16b-3(d) 12,000 -- 109,689
February 19, 2019 CFO Form 4 Grant, award or other acquisition pursuant to Rule 16b-3(d) 20,000 -- 324,951
February 19, 2019 Director Form 4 Grant, award or other acquisition pursuant to Rule 16b-3(d) 12,000 -- 106,118
February 19, 2019 Director Form 4 Grant, award or other acquisition pursuant to Rule 16b-3(d) 12,000 -- 106,118
February 19, 2019 Director Form 4 Grant, award or other acquisition pursuant to Rule 16b-3(d) 12,000 -- 105,880
February 19, 2019 Director, Chairman, President and CEO Form 4 Grant, award or other acquisition pursuant to Rule 16b-3(d) 50,000 -- 1,096,071
February 19, 2019 Controller Form 4 Grant, award or other acquisition pursuant to Rule 16b-3(d) 7,500 -- 107,057
February 19, 2019 Director Form 4 Grant, award or other acquisition pursuant to Rule 16b-3(d) 12,000 -- 77,357
May 15, 2018 Chief Scientific Officer Form 4 Grant, award or other acquisition pursuant to Rule 16b-3(d) 100,000 -- 124,643
May 15, 2018 CMO Form 4 Grant, award or other acquisition pursuant to Rule 16b-3(d) 250,000 -- 305,047
May 15, 2018 Director Form 4 Grant, award or other acquisition pursuant to Rule 16b-3(d) 50,000 -- 65,357
May 15, 2018 Director Form 4 Grant, award or other acquisition pursuant to Rule 16b-3(d) 70,000 -- 97,689
May 15, 2018 CFO Form 4 Grant, award or other acquisition pursuant to Rule 16b-3(d) 250,000 -- 304,951
May 15, 2018 Director Form 4 Grant, award or other acquisition pursuant to Rule 16b-3(d) 70,000 -- 94,118
May 15, 2018 Director Form 4 Grant, award or other acquisition pursuant to Rule 16b-3(d) 70,000 -- 94,118
May 15, 2018 Director Form 4 Grant, award or other acquisition pursuant to Rule 16b-3(d) 70,000 -- 93,880
May 15, 2018 Director, Chairman, President and CEO Form 4 Grant, award or other acquisition pursuant to Rule 16b-3(d) 850,000 -- 1,046,071
May 15, 2018 Controller Form 4 Grant, award or other acquisition pursuant to Rule 16b-3(d) 80,000 -- 99,557
May 15, 2018 Director Form 4 Grant, award or other acquisition pursuant to Rule 16b-3(d) 50,000 -- 65,357
May 30, 2017 Chief Scientific Officer Form 4 Grant, award or other acquisition pursuant to Rule 16b-3(d) 21,786 -- 21,786
May 30, 2017 CMO Form 4 Grant, award or other acquisition pursuant to Rule 16b-3(d) 48,571 -- 48,571
May 30, 2017 Director Form 4 Grant, award or other acquisition pursuant to Rule 16b-3(d) 12,500 -- 12,500

For recent transactions, including derivative transactions, see our Section 16 SEC filings page.

* Represents the number of non-derivative securities directly held. (I) Indicates that some (or all) of these shares are held indirectly.