| Date | Filer | Title | Filing | Type | Shares Traded | Price | Total Held |
|---|---|---|---|---|---|---|---|
| January 19, 2009 | Chief Financial Officer | Form 4 | Grant, award or other acquisition pursuant to Rule 16b-3(d) | 6,667 | $2.72 | 113,334 | |
| January 19, 2009 | Chief Financial Officer | Form 4 | Grant, award or other acquisition pursuant to Rule 16b-3(d) | 6,666 | $2.72 | 120,000 | |
| January 19, 2009 | Chief Financial Officer | Form 4 | Grant, award or other acquisition pursuant to Rule 16b-3(d) | 5,000 | $2.72 | 30,000 | |
| January 19, 2009 | Director | Form 4 | Grant, award or other acquisition pursuant to Rule 16b-3(d) | 8,334 | $2.72 | 69,010 | |
| January 19, 2009 | Director | Form 4 | Grant, award or other acquisition pursuant to Rule 16b-3(d) | 8,333 | $2.72 | 77,343 | |
| January 19, 2009 | Director | Form 4 | Grant, award or other acquisition pursuant to Rule 16b-3(d) | 8,333 | $2.72 | 85,676 | |
| January 19, 2009 | Director, President & CEO | Form 4 | Grant, award or other acquisition pursuant to Rule 16b-3(d) | 25,000 | $2.72 | 530,000 | |
| January 19, 2009 | Director, President & CEO | Form 4 | Grant, award or other acquisition pursuant to Rule 16b-3(d) | 25,000 | $2.72 | 555,000 | |
| January 19, 2009 | Director, President & CEO | Form 4 | Grant, award or other acquisition pursuant to Rule 16b-3(d) | 25,000 | $2.72 | 580,000 | |
| January 19, 2009 | Director, President & CEO | Form 4 | Grant, award or other acquisition pursuant to Rule 16b-3(d) | 8,333 | $2.72 | 40,500 | |
| January 19, 2009 | Director, President & CEO | Form 4 | Grant, award or other acquisition pursuant to Rule 16b-3(d) | 8,333 | $2.72 | 48,833 | |
| January 19, 2009 | Director, President & CEO | Form 4 | Grant, award or other acquisition pursuant to Rule 16b-3(d) | 8,334 | $2.72 | 57,167 | |
| January 19, 2009 | Director | Form 4 | Grant, award or other acquisition pursuant to Rule 16b-3(d) | 8,334 | $2.72 | 65,344 | |
| January 19, 2009 | Director | Form 4 | Grant, award or other acquisition pursuant to Rule 16b-3(d) | 8,333 | $2.72 | 73,677 | |
| January 19, 2009 | Director | Form 4 | Grant, award or other acquisition pursuant to Rule 16b-3(d) | 8,333 | $2.72 | 82,010 | |
| December 8, 2008 | Chief Financial Officer | Form 4 | Grant, award or other acquisition pursuant to Rule 16b-3(d) | 25,000 | $3.00 | 25,000 | |
| December 8, 2008 | Chief Financial Officer | Form 4 | Grant, award or other acquisition pursuant to Rule 16b-3(d) | 100,000 | $3.00 | 100,000 | |
| December 4, 2008 | Director | Form 4 | Open market or private purchase of non-derivative or derivative security | 19,007 | $2.50 | 43,356 | |
| November 20, 2008 | VP & Chief Medical Officer | Form 4 | Open market or private purchase of non-derivative or derivative security | 5,596 | $2.50 | 14,000 | |
| November 19, 2008 | VP & Chief Medical Officer | Form 4 | Open market or private purchase of non-derivative or derivative security | 404 | $2.50 | 8,404 | |
| November 19, 2008 | Director | Form 4 | Open market or private purchase of non-derivative or derivative security | 2,100 | $2.70 | 122,562 | |
| November 17, 2008 | Director | Form 4 | Open market or private purchase of non-derivative or derivative security | 100 | $2.60 | 113,462 | |
| November 17, 2008 | Director | Form 4 | Open market or private purchase of non-derivative or derivative security | 7,000 | $2.76 | 120,462 | |
| November 14, 2008 | Director, President & CEO | Form 4 | Open market or private purchase of non-derivative or derivative security | 3,000 | $2.83 | 32,167 | |
| June 18, 2008 | VP & Chief Medical Officer | Form 4 | Open market or private purchase of non-derivative or derivative security | 3,000 | $4.10 | 8,000 |
For recent transactions, including derivative transactions, see our Section 16 SEC filings page.
* Represents the number of non-derivative securities directly held. (I) Indicates that some (or all) of these shares are held indirectly.
