| Date | Filer | Title | Filing | Type | Shares Traded | Price | Total Held |
|---|---|---|---|---|---|---|---|
| January 16, 2006 | VP of Clinical Development | Form 4 | Grant, award or other acquisition pursuant to Rule 16b-3(d) | 200,000 | -- | 200,000 | |
| November 16, 2005 | EVP, CFO | Form 4 | Open market or private purchase of non-derivative or derivative security | 3,700 | $0.29 | 3,700 | |
| November 16, 2005 | EVP, CFO | Form 4 | Open market or private purchase of non-derivative or derivative security | 21,300 | $0.29 | 21,300 | |
| November 15, 2005 | VP of Operations | Form 4 | Open market or private purchase of non-derivative or derivative security | 20,000 | $0.31 | 20,000 | |
| November 14, 2005 | EVP, CFO | Form 4 | Open market or private purchase of non-derivative or derivative security | 25,000 | $0.32 | 25,000 | |
| November 14, 2005 | President, CEO | Form 4 | Open market or private purchase of non-derivative or derivative security | 76,645 | $0.33 | 76,645 | |
| August 12, 2005 | Director | Form 4 | Grant, award or other acquisition pursuant to Rule 16b-3(d) | 50,000 | -- | 50,000 | |
| July 29, 2005 | President, CEO | Form 4 | Grant, award or other acquisition pursuant to Rule 16b-3(d) | 6,440,000 | -- | 6,440,000 | |
| June 7, 2005 | Director, President and CEO | Form 4 | Bona fide gift | 995,500 | -- | 5,282,676 | |
| June 1, 2005 | Director, President and CEO | Form 4 | Bona fide gift | 1,000,000 | -- | 4,287,176 | |
| May 25, 2005 | VP of Operations | Form 4 | Open market or private purchase of non-derivative or derivative security | 10,000 | $0.39 | 10,000 | |
| May 24, 2005 | Director | Form 4 | Open market or private purchase of non-derivative or derivative security | 55,700 | $0.41 | 720,095 | |
| May 24, 2005 | Director | Form 4 | Open market or private purchase of non-derivative or derivative security | 20,000 | $0.42 | 148,346 | |
| May 23, 2005 | Director | Form 4 | Open market or private purchase of non-derivative or derivative security | 44,300 | $0.40 | 664,395 | |
| February 22, 2005 | Director, President and CEO | Form 4 | Grant, award or other acquisition pursuant to Rule 16b-3(d) | 150,000 | -- | 2,100,000 | |
| February 22, 2005 | Director, Chief Financial Officer | Form 4 | Grant, award or other acquisition pursuant to Rule 16b-3(d) | 100,000 | -- | 1,820,000 | |
| February 22, 2005 | VP, General Counsel | Form 4 | Grant, award or other acquisition pursuant to Rule 16b-3(d) | 100,000 | -- | 300,000 | |
| February 22, 2005 | Director | Form 4 | Grant, award or other acquisition pursuant to Rule 16b-3(d) | 98,684 | -- | 620,095 | |
| February 22, 2005 | Director | Form 4 | Grant, award or other acquisition pursuant to Rule 16b-3(d) | 70,000 | -- | 320,000 | |
| February 22, 2005 | Director | Form 4 | Grant, award or other acquisition pursuant to Rule 16b-3(d) | 55,000 | -- | 105,000 | |
| February 22, 2005 | Director | Form 4 | Grant, award or other acquisition pursuant to Rule 16b-3(d) | 50,000 | -- | 50,000 | |
| February 22, 2005 | Director | Form 4 | Grant, award or other acquisition pursuant to Rule 16b-3(d) | 55,000 | -- | 105,000 | |
| February 22, 2005 | Director | Form 4 | Grant, award or other acquisition pursuant to Rule 16b-3(d) | 55,000 | -- | 216,000 | |
| February 22, 2005 | Director | Form 4 | Grant, award or other acquisition pursuant to Rule 16b-3(d) | 55,000 | -- | 905,000 | |
| June 9, 2004 | Senior Vice President | Form 4 | Grant, award or other acquisition pursuant to Rule 16b-3(d) | 400,000 | -- | 400,000 |
For recent transactions, including derivative transactions, see our Section 16 SEC filings page.
* Represents the number of non-derivative securities directly held. (I) Indicates that some (or all) of these shares are held indirectly.
