Date Filer Title Filing Type Shares Traded Price Total Held
May 30, 2017 Director Form 4 Grant, award or other acquisition pursuant to Rule 16b-3(d) 24,286 -- 24,286
May 30, 2017 CFO Form 4 Grant, award or other acquisition pursuant to Rule 16b-3(d) 48,571 -- 48,571
May 30, 2017 Director Form 4 Grant, award or other acquisition pursuant to Rule 16b-3(d) 21,429 -- 21,429
May 30, 2017 Director Form 4 Grant, award or other acquisition pursuant to Rule 16b-3(d) 21,429 -- 21,249
May 30, 2017 Director Form 4 Grant, award or other acquisition pursuant to Rule 16b-3(d) 21,429 -- 21,429
May 30, 2017 Director, Chairman, President and CEO Form 4 Grant, award or other acquisition pursuant to Rule 16b-3(d) 176,429 -- 176,429
May 30, 2017 Controller Form 4 Grant, award or other acquisition pursuant to Rule 16b-3(d) 17,143 -- 17,143
May 30, 2017 Director Form 4 Grant, award or other acquisition pursuant to Rule 16b-3(d) 12,500 -- 12,500
September 6, 2016 CMO Form 4 Grant, award or other acquisition pursuant to Rule 16b-3(d) 40,663 -- 316,213
September 6, 2016 Director Form 4 Grant, award or other acquisition pursuant to Rule 16b-3(d) 22,664 -- 158,215
September 6, 2016 CFO Form 4 Grant, award or other acquisition pursuant to Rule 16b-3(d) 29,332 -- 305,996
September 6, 2016 Director Form 4 Grant, award or other acquisition pursuant to Rule 16b-3(d) 7,332 -- 117,330
September 6, 2016 Director Form 4 Grant, award or other acquisition pursuant to Rule 16b-3(d) 12,665 -- 131,551
September 6, 2016 Director Form 4 Grant, award or other acquisition pursuant to Rule 16b-3(d) 9,332 -- 122,663
September 6, 2016 Director, Chairman, President and CEO Form 4 Grant, award or other acquisition pursuant to Rule 16b-3(d) 125,000 -- 923,885
September 6, 2016 Controller Form 4 Grant, award or other acquisition pursuant to Rule 16b-3(d) 13,816 -- 115,573
February 2, 2016 Chief Scientific Officer Form 4 Grant, award or other acquisition pursuant to Rule 16b-3(d) 40,000 -- 152,500
February 2, 2016 CMO Form 4 Grant, award or other acquisition pursuant to Rule 16b-3(d) 50,000 -- 275,550
February 2, 2016 Director Form 4 Grant, award or other acquisition pursuant to Rule 16b-3(d) 25,000 -- 135,551
February 2, 2016 CFO Form 4 Grant, award or other acquisition pursuant to Rule 16b-3(d) 60,000 -- 276,664
February 2, 2016 Director Form 4 Grant, award or other acquisition pursuant to Rule 16b-3(d) 25,000 -- 109,998
February 2, 2016 Director Form 4 Grant, award or other acquisition pursuant to Rule 16b-3(d) 25,000 -- 118,886
February 2, 2016 Director Form 4 Grant, award or other acquisition pursuant to Rule 16b-3(d) 25,000 -- 113,331
February 2, 2016 Director, CEO Form 4 Grant, award or other acquisition pursuant to Rule 16b-3(d) 150,000 -- 798,885
February 2, 2016 Controller Form 4 Grant, award or other acquisition pursuant to Rule 16b-3(d) 20,000 -- 101,757

For recent transactions, including derivative transactions, see our Section 16 SEC filings page.

* Represents the number of non-derivative securities directly held. (I) Indicates that some (or all) of these shares are held indirectly.