Date Filer Title Filing Type Shares Traded Price Total Held
February 22, 2012 Director Form 4 Grant, award or other acquisition pursuant to Rule 16b-3(d) 25,000 -- 55,000
February 22, 2012 Director Form 4 Grant, award or other acquisition pursuant to Rule 16b-3(d) 25,000 -- 95,000
February 22, 2012 Director Form 4 Grant, award or other acquisition pursuant to Rule 16b-3(d) 35,000 -- 254,911
February 22, 2012 Director Form 4 Grant, award or other acquisition pursuant to Rule 16b-3(d) 25,000 -- 70,000
February 22, 2012 CEO Form 4 Grant, award or other acquisition pursuant to Rule 16b-3(d) 33,000 -- 878,000
August 9, 2011 Director Form 4 Conversion of derivative security 41 -- --
July 12, 2011 Director Form 3 Initial Statement of Beneficial Ownership of Securities -- -- 2,000
March 23, 2011 CMO Form 4 Conversion of derivative security 6 -- --
March 23, 2011 CFO Form 4 Conversion of derivative security 8 -- --
March 23, 2011 Director Form 4 Conversion of derivative security 12 -- --
March 23, 2011 Director Form 4 Conversion of derivative security 83 -- --
March 23, 2011 CEO Form 4 Conversion of derivative security 41 -- --
March 23, 2011 Controller & CAO Form 4 Conversion of derivative security 8 -- --
February 25, 2011 CFO Form 4 Grant, award or other acquisition pursuant to Rule 16b-3(d) 10,000 -- 35,000
January 14, 2011 Chief Medical Officer Form 4 Open market or private purchase of non-derivative or derivative security 2,499 -- 2,500
January 14, 2011 CFO Form 4 Open market or private purchase of non-derivative or derivative security 3,333 -- 3,333
January 14, 2011 Director Form 4 Open market or private purchase of non-derivative or derivative security 4,999 -- 5,000
January 14, 2011 Director Form 4 Open market or private purchase of non-derivative or derivative security 17,083 -- 17,083
January 14, 2011 Director Form 4 Open market or private purchase of non-derivative or derivative security 34,583 -- 34,583
January 14, 2011 CEO Form 4 Open market or private purchase of non-derivative or derivative security 17,083 -- 17,083
January 14, 2011 Controller & CAO Form 4 Open market or private purchase of non-derivative or derivative security 3,333 -- 3,333
July 6, 2010 Chief Financial Officer Form 4 Grant, award or other acquisition pursuant to Rule 16b-3(d) 25,000 -- 25,000
April 13, 2010 Interim Chief Accounting Off. Form 4 Exercise or conversion of derivative security exempted pursuant to Rule 16b-3 700 -- 7,700
April 13, 2010 Interim Chief Accounting Off. Form 4 Exercise or conversion of derivative security exempted pursuant to Rule 16b-3 700 -- 21,400
January 19, 2010 Chief Executive Officer Form 4 Exercise or conversion of derivative security exempted pursuant to Rule 16b-3 16,667 -- 114,329

For recent transactions, including derivative transactions, see our Section 16 SEC filings page.

* Represents the number of non-derivative securities directly held. (I) Indicates that some (or all) of these shares are held indirectly.