| Date | Filer | Title | Filing | Type | Shares Traded | Price | Total Held |
|---|---|---|---|---|---|---|---|
| February 19, 2019 | Director | Form 4 | Grant, award or other acquisition pursuant to Rule 16b-3(d) | 12,000 | -- | 77,357 | |
| May 15, 2018 | Chief Scientific Officer | Form 4 | Grant, award or other acquisition pursuant to Rule 16b-3(d) | 100,000 | -- | 124,643 | |
| May 15, 2018 | CMO | Form 4 | Grant, award or other acquisition pursuant to Rule 16b-3(d) | 250,000 | -- | 305,047 | |
| May 15, 2018 | Director | Form 4 | Grant, award or other acquisition pursuant to Rule 16b-3(d) | 50,000 | -- | 65,357 | |
| May 15, 2018 | Director | Form 4 | Grant, award or other acquisition pursuant to Rule 16b-3(d) | 70,000 | -- | 97,689 | |
| May 15, 2018 | CFO | Form 4 | Grant, award or other acquisition pursuant to Rule 16b-3(d) | 250,000 | -- | 304,951 | |
| May 15, 2018 | Director | Form 4 | Grant, award or other acquisition pursuant to Rule 16b-3(d) | 70,000 | -- | 94,118 | |
| May 15, 2018 | Director | Form 4 | Grant, award or other acquisition pursuant to Rule 16b-3(d) | 70,000 | -- | 94,118 | |
| May 15, 2018 | Director | Form 4 | Grant, award or other acquisition pursuant to Rule 16b-3(d) | 70,000 | -- | 93,880 | |
| May 15, 2018 | Director, Chairman, President and CEO | Form 4 | Grant, award or other acquisition pursuant to Rule 16b-3(d) | 850,000 | -- | 1,046,071 | |
| May 15, 2018 | Controller | Form 4 | Grant, award or other acquisition pursuant to Rule 16b-3(d) | 80,000 | -- | 99,557 | |
| May 15, 2018 | Director | Form 4 | Grant, award or other acquisition pursuant to Rule 16b-3(d) | 50,000 | -- | 65,357 | |
| May 30, 2017 | Chief Scientific Officer | Form 4 | Grant, award or other acquisition pursuant to Rule 16b-3(d) | 21,786 | -- | 21,786 | |
| May 30, 2017 | CMO | Form 4 | Grant, award or other acquisition pursuant to Rule 16b-3(d) | 48,571 | -- | 48,571 | |
| May 30, 2017 | Director | Form 4 | Grant, award or other acquisition pursuant to Rule 16b-3(d) | 12,500 | -- | 12,500 | |
| May 30, 2017 | Director | Form 4 | Grant, award or other acquisition pursuant to Rule 16b-3(d) | 24,286 | -- | 24,286 | |
| May 30, 2017 | CFO | Form 4 | Grant, award or other acquisition pursuant to Rule 16b-3(d) | 48,571 | -- | 48,571 | |
| May 30, 2017 | Director | Form 4 | Grant, award or other acquisition pursuant to Rule 16b-3(d) | 21,429 | -- | 21,429 | |
| May 30, 2017 | Director | Form 4 | Grant, award or other acquisition pursuant to Rule 16b-3(d) | 21,429 | -- | 21,249 | |
| May 30, 2017 | Director | Form 4 | Grant, award or other acquisition pursuant to Rule 16b-3(d) | 21,429 | -- | 21,429 | |
| May 30, 2017 | Director, Chairman, President and CEO | Form 4 | Grant, award or other acquisition pursuant to Rule 16b-3(d) | 176,429 | -- | 176,429 | |
| May 30, 2017 | Controller | Form 4 | Grant, award or other acquisition pursuant to Rule 16b-3(d) | 17,143 | -- | 17,143 | |
| May 30, 2017 | Director | Form 4 | Grant, award or other acquisition pursuant to Rule 16b-3(d) | 12,500 | -- | 12,500 | |
| September 6, 2016 | CMO | Form 4 | Grant, award or other acquisition pursuant to Rule 16b-3(d) | 40,663 | -- | 316,213 | |
| September 6, 2016 | Director | Form 4 | Grant, award or other acquisition pursuant to Rule 16b-3(d) | 22,664 | -- | 158,215 |
For recent transactions, including derivative transactions, see our Section 16 SEC filings page.
* Represents the number of non-derivative securities directly held. (I) Indicates that some (or all) of these shares are held indirectly.
