Date Filer Title Filing Type Shares Traded Price Total Held
October 9, 2007
VENKAT KRIS
 Director Form 4 Open market or private purchase of non-derivative or derivative security 5,000 $5.84 109,010
May 18, 2007
LINK MAX
 Director Form 4 Open market or private purchase of non-derivative or derivative security 10,000 $4.84 113,362
May 17, 2007
Tardugno Michael H
 President, CEO Form 4 Open market or private purchase of non-derivative or derivative security 1,784 $4.81 9,400
May 17, 2007
Tardugno Michael H
 President, CEO Form 4 Open market or private purchase of non-derivative or derivative security 600 $4.82 10,000
March 22, 2007
LINK MAX
 Director Form 4 Open market or private purchase of non-derivative or derivative security 35,000 -- 64,912
March 12, 2007
Chow Pok Yu Augustine
 Director Form 4 Open market or private purchase of non-derivative or derivative security 30,000 $4.55 30,000
February 27, 2007
LINK MAX
 Director Form 4 Open market or private purchase of non-derivative or derivative security 10,000 $3.49 97,466
February 26, 2007
LINK MAX
 Director Form 4 Open market or private purchase of non-derivative or derivative security 10,000 $3.50 87,466
February 23, 2007
Hahne William
 VP of Research & Development Form 4 Open market or private purchase of non-derivative or derivative security 6,000 $3.55 15,100
February 23, 2007
Tardugno Michael H
 President, CEO Form 4 Open market or private purchase of non-derivative or derivative security 7,616 $3.46 7,616
February 23, 2007
WEAVER GREGORY L
 Director Form 4 Open market or private purchase of non-derivative or derivative security 10,000 $3.50 10,000
October 3, 2006
Hahne William
 VP of Research & Development Form 4 Open market or private purchase of non-derivative or derivative security 5,100 -- 18,434
May 12, 2006
Hahne William
 VP - Clin. Dev. & Med. Affairs Form 4 Open market or private purchase of non-derivative or derivative security 300 $3.75 2,300
May 12, 2006
Hahne William
 VP - Clin. Dev. & Med. Affairs Form 4 Open market or private purchase of non-derivative or derivative security 1,700 $3.75 4,000
March 20, 2006
Hahne William
 VP - Clin. Dev. & Med. Affairs Form 4 Open market or private purchase of non-derivative or derivative security 800 $4.20 1,800
March 20, 2006
Hahne William
 VP - Clin. Dev. & Med. Affairs Form 4 Open market or private purchase of non-derivative or derivative security 200 $4.19 2,000
March 17, 2006
LINK MAX
 Director Form 4 Open market or private purchase of non-derivative or derivative security 10,000 $4.03 70,800
March 15, 2006
LINK MAX
 Director Form 4 Open market or private purchase of non-derivative or derivative security 8,578 -- 29,912
March 14, 2006
Hahne William
 Director Form 4 Open market or private purchase of non-derivative or derivative security 200 $4.05 200
March 14, 2006
Hahne William
 Director Form 4 Open market or private purchase of non-derivative or derivative security 800 $4.05 1,000
March 14, 2006
Hahne William
 VP - Clin. Dev. & Med. Affairs Form 4/A Open market or private purchase of non-derivative or derivative security 200 $4.05 200
March 14, 2006
Hahne William
 VP - Clin. Dev. & Med. Affairs Form 4/A Open market or private purchase of non-derivative or derivative security 800 $4.05 1,000
March 3, 2006
DEASEY ANTHONY P
 EVP, CFO Form 4 Open market or private purchase of non-derivative or derivative security 2,500 $4.28 17,944
November 17, 2005
DEASEY ANTHONY P
 EVP, CFO Form 4/A Open market or private purchase of non-derivative or derivative security 21,300 $0.29 231,667
November 16, 2005
DEASEY ANTHONY P
 EVP, CFO Form 4/A Open market or private purchase of non-derivative or derivative security 3,700 $0.29 210,367

For recent transactions, including derivative transactions, see our Section 16 SEC filings page.

* Represents the number of non-derivative securities directly held. (I) Indicates that some (or all) of these shares are held indirectly.