Date Filer Title Filing Type Shares Traded Price Total Held
October 29, 2007 Chief Accounting Officer Form 4 Open market or private purchase of non-derivative or derivative security 1,666 $6.10 15,000
October 29, 2007 Chief Accounting Officer Form 4 Open market or private purchase of non-derivative or derivative security 1,666 $6.10 15,000
October 9, 2007 Director Form 4 Open market or private purchase of non-derivative or derivative security 5,000 $5.84 104,010
October 9, 2007 Director Form 4 Open market or private purchase of non-derivative or derivative security 5,000 $5.84 109,010
May 18, 2007 Director Form 4 Open market or private purchase of non-derivative or derivative security 10,000 $4.84 113,362
May 17, 2007 President, CEO Form 4 Open market or private purchase of non-derivative or derivative security 1,784 $4.81 9,400
May 17, 2007 President, CEO Form 4 Open market or private purchase of non-derivative or derivative security 600 $4.82 10,000
March 22, 2007 Director Form 4 Open market or private purchase of non-derivative or derivative security 35,000 -- 64,912
March 22, 2007 Director Form 4 Grant, award or other acquisition pursuant to Rule 16b-3(d) 25,000 -- 35,676
March 22, 2007 Director Form 4 Grant, award or other acquisition pursuant to Rule 16b-3(d) 25,000 -- 99,010
March 22, 2007 Director Form 4 Grant, award or other acquisition pursuant to Rule 16b-3(d) 25,000 -- 32,010
March 15, 2007 VP of Research & Development Form 4 Grant, award or other acquisition pursuant to Rule 16b-3(d) 15,000 -- 33,434
March 14, 2007 Director Form 3 Initial Statement of Beneficial Ownership of Securities -- -- --
March 12, 2007 Director Form 4 Open market or private purchase of non-derivative or derivative security 30,000 $4.55 30,000
February 27, 2007 Director Form 4 Grant, award or other acquisition pursuant to Rule 16b-3(d) 5,896 -- 103,362
February 27, 2007 Director Form 4 Open market or private purchase of non-derivative or derivative security 10,000 $3.49 97,466
February 26, 2007 Director Form 4 Open market or private purchase of non-derivative or derivative security 10,000 $3.50 87,466
February 23, 2007 VP of Research & Development Form 4 Open market or private purchase of non-derivative or derivative security 6,000 $3.55 15,100
February 23, 2007 President, CEO Form 4 Open market or private purchase of non-derivative or derivative security 7,616 $3.46 7,616
February 23, 2007 Director Form 4 Open market or private purchase of non-derivative or derivative security 10,000 $3.50 10,000
January 3, 2007 President, CEO Form 4 Grant, award or other acquisition pursuant to Rule 16b-3(d) 430,000 $2.42 430,000
January 3, 2007 President, CEO Form 4 Grant, award or other acquisition pursuant to Rule 16b-3(d) 50,000 $2.42 480,000
October 3, 2006 VP of Research & Development Form 4 Grant, award or other acquisition pursuant to Rule 16b-3(d) 5,100 $2.44 9,100
October 3, 2006 VP of Research & Development Form 4 Open market or private purchase of non-derivative or derivative security 5,100 -- 18,434
May 12, 2006 VP - Clin. Dev. & Med. Affairs Form 4 Open market or private purchase of non-derivative or derivative security 300 $3.75 2,300

For recent transactions, including derivative transactions, see our Section 16 SEC filings page.

* Represents the number of non-derivative securities directly held. (I) Indicates that some (or all) of these shares are held indirectly.