Date Filer Title Filing Type Shares Traded Price Total Held
December 4, 2008 Director Form 4 Open market or private purchase of non-derivative or derivative security 19,007 $2.50 43,356
November 20, 2008 VP & Chief Medical Officer Form 4 Open market or private purchase of non-derivative or derivative security 5,596 $2.50 14,000
November 19, 2008 VP & Chief Medical Officer Form 4 Open market or private purchase of non-derivative or derivative security 404 $2.50 8,404
November 19, 2008 Director Form 4 Open market or private purchase of non-derivative or derivative security 2,100 $2.70 122,562
November 17, 2008 Director Form 4 Open market or private purchase of non-derivative or derivative security 100 $2.60 113,462
November 17, 2008 Director Form 4 Open market or private purchase of non-derivative or derivative security 7,000 $2.76 120,462
November 14, 2008 Director, President & CEO Form 4 Open market or private purchase of non-derivative or derivative security 3,000 $2.83 32,167
June 18, 2008 VP & Chief Medical Officer Form 4 Open market or private purchase of non-derivative or derivative security 3,000 $4.10 8,000
June 17, 2008 VP & Chief Medical Officer Form 3 Initial Statement of Beneficial Ownership of Securities -- -- 5,000
June 17, 2008 VP & Chief Medical Officer Form 3 Initial Statement of Beneficial Ownership of Securities -- -- --
June 17, 2008 VP & Chief Medical Officer Form 3 Initial Statement of Beneficial Ownership of Securities -- -- --
June 17, 2008 VP & Chief Medical Officer Form 3 Initial Statement of Beneficial Ownership of Securities -- -- --
June 17, 2008 VP & Chief Medical Officer Form 3 Initial Statement of Beneficial Ownership of Securities -- -- --
June 17, 2008 VP & Chief Medical Officer Form 3 Initial Statement of Beneficial Ownership of Securities -- -- --
June 17, 2008 VP & Chief Medical Officer Form 3 Initial Statement of Beneficial Ownership of Securities -- -- --
June 17, 2008 VP & Chief Medical Officer Form 3 Initial Statement of Beneficial Ownership of Securities -- -- --
June 16, 2008 Director, President & CEO Form 4/A Open market or private purchase of non-derivative or derivative security 400 $4.38 27,067
June 16, 2008 Director, President & CEO Form 4/A Open market or private purchase of non-derivative or derivative security 300 $4.39 27,367
June 16, 2008 Director, President & CEO Form 4/A Open market or private purchase of non-derivative or derivative security 1,800 $4.40 29,167
June 16, 2008 Director, President & CEO Form 4 Grant, award or other acquisition pursuant to Rule 16b-3(d) 400 $4.38 27,067
June 16, 2008 Director, President & CEO Form 4 Grant, award or other acquisition pursuant to Rule 16b-3(d) 300 $4.39 27,367
June 16, 2008 Director, President & CEO Form 4 Grant, award or other acquisition pursuant to Rule 16b-3(d) 1,800 $4.40 29,167
March 15, 2008 Director Form 4 Grant, award or other acquisition pursuant to Rule 16b-3(d) 8,333 $5.47 38,333
March 15, 2008 Director Form 4 Grant, award or other acquisition pursuant to Rule 16b-3(d) 8,333 $5.47 46,666
March 15, 2008 Director Form 4 Grant, award or other acquisition pursuant to Rule 16b-3(d) 8,334 $5.47 55,000

For recent transactions, including derivative transactions, see our Section 16 SEC filings page.

* Represents the number of non-derivative securities directly held. (I) Indicates that some (or all) of these shares are held indirectly.